{"created":"2025-04-01T20:43:41.706295+00:00","id":2012338,"links":{},"metadata":{"_buckets":{"deposit":"f47aef34-cbbf-4699-92a3-84f22cb23410"},"_deposit":{"id":"2012338","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"2012338"},"status":"published"},"_oai":{"id":"oai:teikyo-u.repo.nii.ac.jp:02012338","sets":["1726879085919:1741828256493"]},"author_link":[],"item_1551264308487":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_title":"Prediction of early response to uterine artery embolization in fibroids: class FormattedString {\n value: Value of MR signal intensity ratio\n}","subitem_title_language":"eng"}]},"item_1551264340087":{"attribute_name":"Creator","attribute_type":"creator","attribute_value_mlt":[{"familyNames":[{"familyName":"Noda"}],"givenNames":[{"givenName":"Yoshifumi"}]},{"familyNames":[{"familyName":"Kanematsu"}],"givenNames":[{"givenName":"Masayuki"}]},{"familyNames":[{"familyName":"Goshima"}],"givenNames":[{"givenName":"Satoshi"}]},{"familyNames":[{"familyName":"kondou","familyNameLang":"eng"},{"familyName":"近藤","familyNameLang":"jpn"}],"givenNames":[{"givenName":"hiroshi","givenNameLang":"eng"},{"givenName":"浩史","givenNameLang":"jpn"}]},{"familyNames":[{"familyName":"Watanabe"}],"givenNames":[{"givenName":"Haruo"}]},{"familyNames":[{"familyName":"Kawada"}],"givenNames":[{"givenName":"Hiroshi"}]},{"familyNames":[{"familyName":"Kawai"}],"givenNames":[{"givenName":"Nobuyuki"}]},{"familyNames":[{"familyName":"Tanahashi"}],"givenNames":[{"givenName":"Yukichi"}]},{"familyNames":[{"familyName":"Bae"}],"givenNames":[{"givenName":"Kyongtae T."}]}]},"item_1551264447183":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_16ec"}]},"item_1551264822581":{"attribute_name":"Subject","attribute_value_mlt":[{"subitem_subject":"Magnetic resonance imaging","subitem_subject_language":"eng","subitem_subject_scheme":"Other"},{"subitem_subject":"Signal intensity ratio","subitem_subject_language":"eng","subitem_subject_scheme":"Other"},{"subitem_subject":"Uterine artery embolization","subitem_subject_language":"eng","subitem_subject_scheme":"Other"},{"subitem_subject":"Uterine fibroid","subitem_subject_language":"eng","subitem_subject_scheme":"Other"},{"subitem_subject":"Biophysics","subitem_subject_language":"eng","subitem_subject_scheme":"SciVal"},{"subitem_subject":"生物理学","subitem_subject_language":"jpn","subitem_subject_scheme":"SciVal"},{"subitem_subject":"Biomedical Engineering","subitem_subject_language":"eng","subitem_subject_scheme":"SciVal"},{"subitem_subject":"生体医工学","subitem_subject_language":"jpn","subitem_subject_scheme":"SciVal"},{"subitem_subject":"Radiology Nuclear Medicine and imaging","subitem_subject_language":"eng","subitem_subject_scheme":"SciVal"},{"subitem_subject":"放射線学、核医学およびイメージング","subitem_subject_language":"jpn","subitem_subject_scheme":"SciVal"},{"subitem_subject":"SDG 3 - Good Health and Well-being","subitem_subject_language":"eng","subitem_subject_scheme":"SDG"},{"subitem_subject":"SDG 3 - すべての人に健康と福祉を","subitem_subject_language":"jpn","subitem_subject_scheme":"SDG"}]},"item_1551264846237":{"attribute_name":"Description","attribute_value_mlt":[{"subitem_description":"

Objective: To quantitatively assess magnetic resonance (MR) imaging findings that help predict early post-therapeutic response in fibroids following uterine artery embolization (UAE). Methods: Fifteen patients with a total of 52 fibroids underwent UAE. The signal intensity ratio (SIR) on T1-, T2-, diffusion weighted and gadolinium-enhanced images was calculated by dividing the mean signal intensity of fibroids by that of the abdominal rectus muscle. Fibroids were divided into the two groups: affected (post-UAE volume reduction rate > median of all fibroids) and unaffected (< median rate). The SIRs were compared between the two groups. ROC analysis was used to evaluate the predictive performance for differentiating the affected from unaffected lesions. Results: The SIRs of the affected group were significantly lower on T1-weighted images (0.85 ± 0.1 vs 0.95 ± 0.2) (P = 0.0001), but higher on T2-weighted (1.30 ± 0.6 vs 1.12 ± 0.9) (P = 0.026) and gadolinium-enhanced images (1.51 ± 0.2 vs 1.20 ± 0.4) (P = 0.0002) than those of the unaffected group. There was no significant difference in ADC values between the two groups (P = 0.510). The sensitivity, specificity, and area under the ROC curve (AUC) in the prediction of the affected lesions were 92%, 50%, and 0.712 with SIR on T1-weighted images, and 85%, 62%, and 0.731 with SIR on gadolinium-enhanced images, respectively. Conclusions: The SIRs on T1-weighted images and gadolinium-enhanced images were useful for the prediction of the changes in size of fibroids responding to UAE.

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